A Method for Predicting Protein-Protein Interaction Types

اسناد مشابه

• A Method for Predicting Protein-Protein Interaction Types

  سند علمی۲۰۱۴PloS oneYael Silberberg, Martin Kupiec, Roded Sharan

  Protein-protein interactions (PPIs) govern basic cellular processes through signal transduction and complex formation. The diversity of those processes gives rise to a remarkable diversity of interactions types, ranging from transient phosphorylation interactions to stable covale

• Kernel methods for predicting protein-protein interactions

  سند علمی۲۰۰۵BioinformaticsAsa Ben-Hur, William Stafford Noble

  MOTIVATION Despite advances in high-throughput methods for discovering protein-protein interactions, the interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experimentalists in the

• Predicting Protein-Protein Interaction by the Mirrortree Method: Possibilities and Limitations

  سند علمی۲۰۱۳PloS oneHua Zhou, Eric Jakobsson

  Molecular co-evolution analysis as a sequence-only based method has been used to predict protein-protein interactions. In co-evolution analysis, Pearson's correlation within the mirrortree method is a well-known way of quantifying the correlation between protein pairs. Here we st

• Nouvelles méthodes de calcul pour la prédiction des interactions protéine-protéine au niveau structural. (Novel computational methods to predict protein-protein interactions on the structural level)

  سند علمی۲۰۱۵Petr Popov

  Drug discovery is a multidisciplinary field which includes molecular biology, biophysics, biochemistry, and pharmacology. It usually starts with the identification of a biological target which is known to play a critical role in a particular disease. Therein, computational method

• FIS-PNN: A HYBRID COMPUTATIONAL METHOD FOR PROTEIN- PROTEIN INTERACTIONS PREDICTION USING THE SECONDARY STRUCTURE INFORMATION (FIS-PNN: Suatu Kaedah Pengkomputeran Hibrid bagi Ramalan Interaksi Protein-Protein Menggunakan Maklumat Struktur Sekunder)

  سند علمی۲۰۱۳SAKHINAH ABU BAKAR, Sakhinah Abu Bakar, Javid Taheri, Albert Y Zomaya

  The study of protein-protein interactions (PPI) is an active area of research in biology because it mediates most of the biological functions in any organism. This work is inspired by the fact that proteins with similar secondary structures mostly share very similar three-dimensi

• Computational methods using weighed-extreme learning machine to predict protein self-interactions with protein evolutionary information

  سند علمی۲۰۱۷Journal of cheminformaticsJi-Yong An, Lei Zhang, Yong Zhou, Yu-Jun Zhao

  Self-interactions Proteins (SIPs) is important for their biological activity owing to the inherent interaction amongst their secondary structures or domains. However, due to the limitations of experimental Self-interactions detection, one major challenge in the study of predictio