A method for selecting streptomycin-sensitive mutants of R factors which adenylate streptomycin
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منابع مشابه
Accumulation of 14C-streptomycin by streptomycin-sensitive and streptomycin-resistant group H streptococci.
Three streptomycin-resistant mutants of group H streptococcus, strain Challis, were examined for ability to accumulate (14)C-streptomycin. Although the mutants exhibited different levels of transformation, only the streptomycin-sensitive parent Challis strain accumulated significant amounts of (14)C-streptomycin. It appears that impermeability to streptomycin does not necessarily result in redu...
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Cell-free extracts of Streptomyces bikiniensis contain an adenosine 5'-triphosphate-dependent kinase which inactivates streptomycin (Sm) and dihydrostreptomycin by phosphorylation. The products have been identified as streptomycin 6-phosphate and dihydrostreptomycin 6-phosphate. Activity was not present in logarithmic-phase cells, which were susceptible to 25 mug of Sm per ml. In stationary-pha...
متن کاملStreptomycin
ever, certain adjuvants, e.g. para-aminosalicylic acid, may delay the development of drug-resistance. Streptomycin is not absorbed from the alimentary tract and, therefore, it must always be given intramuscularly as well as directly, where possible, into the spaces which it is desired to render free from bacteria. The drug is excreted by the kidney. After intramuscular injection an adequate blo...
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THIS book is a practical guide wlhiclh deals with imiost of the cond(litionis which come wvithin the scope of plastic surgery as practised in the British Isles. The first six chapters arc devoted to basic principles such as the' use of free skin grafts, flaps and tube pedicles, transplantation of tissues othelthan skini and the treatment of wounds, burns, frostbite, scars and(i keloids. The nex...
متن کاملHeterogeneous character of streptomycin-dependent mutants of a Mycobacterium.
It has recently been shown that streptomycin-dependent variants from certain species of microorganisms differ from the original parent type in colony morphology, growth rate, and pigment production, but in other species no visible differences are observed (Yegian and Budd, 1948; Yegian and Vanderlinde, 1950). Until the present report all of the streptomycin-dependent mutants studied have been f...
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ژورنال
عنوان ژورنال: Genetical Research
سال: 1969
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672300002147