A non-toxic dose of cobalt chloride blocks hair cells of the zebrafish lateral line
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چکیده
منابع مشابه
Zebrafish yap1 plays a role in differentiation of hair cells in posterior lateral line
The evolutionarily conserved Hippo signaling pathway controls organ size by regulating cell proliferation and apoptosis and this process involves Yap1. The zebrafish Yap1 acts during neural differentiation, but its function is not fully understood. The detailed analysis of yap1 expression in proliferative regions, revealed it in the otic placode that gives rise to the lateral line system affect...
متن کاملPatch-clamp recordings from lateral line neuromast hair cells of the living zebrafish.
Zebrafish are popular models for biological discovery. For investigators of the auditory and vestibular periphery, manipulations of hair cell and synaptic mechanisms have relied on inferences from extracellular recordings of physiological activity. We now provide data showing that hair cells and supporting cells of the lateral line can be directly patch-clamped, providing the first recordings o...
متن کاملProliferative Regeneration of Zebrafish Lateral Line Hair Cells after Different Ototoxic Insults
Sensory hair cells in the zebrafish lateral line regenerate rapidly and completely after damage. Previous studies have used a variety of ototoxins to kill lateral line hair cells to study different phenomena including mechanisms of hair cell death and regeneration. We sought to directly compare these ototoxins to determine if they differentially affected the rate and amount of hair cell replace...
متن کاملa corpus-based study of the frequency of personal pronouns in translated and comparable non-translated persian texts
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15 صفحه اولRheotaxis in Larval Zebrafish Is Mediated by Lateral Line Mechanosensory Hair Cells
The lateral line sensory system, found in fish and amphibians, is used in prey detection, predator avoidance and schooling behavior. This system includes cell clusters, called superficial neuromasts, located on the surface of head and trunk of developing larvae. Mechanosensory hair cells in the center of each neuromast respond to disturbances in the water and convey information to the brain via...
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ژورنال
عنوان ژورنال: Hearing Research
سال: 2017
ISSN: 0378-5955
DOI: 10.1016/j.heares.2017.04.001