A novel means of comparing the bioequivalence of two formulations of tripotassium dicitrato bismuthate (De-Noltab).
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چکیده
منابع مشابه
A novel means of comparing the bioequivalence of two formulations of tripotassium dicitrato bismuthate (De-Noltab).
Tripotassium dicitrato-bismuthate (TDB) has a topical action in the upper gastrointestinal tract. Absorption is minimal and the blood levels are therefore irrelevant to the assessment of bioavailability. TDB is however detectable in the stomach and duodenum by conventional electron microscopy. Following oral administration of two different formulations of TDB tables to patients attending a gast...
متن کاملA novel means of comparing the bioequivalence of two formulations of tripotassium dicitrato bismuthate
Tripotassium dicitrato-bismuthate (TDB) has a topical action in the upper gastrointestinal tract. Absorption is minimal and the blood levels are therefore irrelevant to the assessment of bioavailability. TDB is however detectable in the stomach and duodenum by conventional electron microscopy. Following oral administration of two different formulations of TDB tablets to patients attending a gas...
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Fifty patients with endoscopically proven gastric ulcers completed a one month double-blind randomised trial of tripotassium dicitrato bismuthate (TBD) (DeNol) compared with an identical placebo. Ulcer healing occurred in 18 (72%) of the 25 patients given TDB and in nine (36%) of the patients given placebo. The TDB group experienced significantly less pain than the placebo group. During a follo...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1988
ISSN: 0032-5473
DOI: 10.1136/pgmj.64.756.761