A novel polyrotaxane-based delivery system for scutellarin: preparation, characterization, and in vitro evaluation
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چکیده
منابع مشابه
Preparation and in vitro evaluation of a novel chitosan-based hydrogel for injectable delivery of enrofloxacin
BACKGROUND: The development of injectable sustained-release products are of great interest to veterinary pharmaceuticals and animal health business. Recently, great attention has been paid to in situ gel-forming chitosan/beta-glycerophosphate (chitosan/β-GP) solutions due to their good biodegradability and thermosensitivity. OBJECTIVES: The general aim of this study was to prepare a novel in si...
متن کاملA novel polyrotaxane-based intracellular delivery system for camptothecin: in vitro feasibility evaluation.
Camptothecin (CPT) is a naturally occurring alkaloid that shows promise in antitumor activity in vitro against various tumor cell lines. Its potential clinical uses, however, are hindered by a lack of reaction selectivity and poor water solubility. Presented herein is a novel polyrotaxane (PR)-based delivery system that could potentially lead to a highly effective yet less toxic CPT therapy. Th...
متن کاملPreparation and In Vitro Evaluation of a Microballoon Delivery System for Theophylline
A multiple-unit oral floating system was prepared using the emulsification-solvent diffusion method to prolong the gastric emptying time of theophylline. For this purpose, theophylline, ethyl cellulose and dibutyl phthalate were dissolved in an ethanol/dichloromethane mixture, added to 0.1 M HCl containing NaCl (20%) or saturated theophylline and/or different concentrations of polysorbate 80 an...
متن کاملPreparation and In Vitro Evaluation of a Microballoon Delivery System for Theophylline
A multiple-unit oral floating system was prepared using the emulsification-solvent diffusion method to prolong the gastric emptying time of theophylline. For this purpose, theophylline, ethyl cellulose and dibutyl phthalate were dissolved in an ethanol/dichloromethane mixture, added to 0.1 M HCl containing NaCl (20%) or saturated theophylline and/or different concentrations of polysorbate 80 an...
متن کاملpreparation and in vitro evaluation of a novel chitosan-based hydrogel for injectable delivery of enrofloxacin
background: the development of injectable sustained-release products are of great interest to veterinary pharmaceuticals and animal health business. recently, great attention has been paid to in situ gel-forming chitosan/beta-glycerophosphate (chitosan/β-gp) solutions due to their good biodegradability and thermosensitivity. objectives: the general aim of this study was to prepare a novel in si...
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ژورنال
عنوان ژورنال: Carbohydrate Research
سال: 2013
ISSN: 0008-6215
DOI: 10.1016/j.carres.2013.07.009