A Partial Volume Effect Correction Tailored for18F-FDG-PET Oncological Studies
نویسندگان
چکیده
منابع مشابه
A Partial Volume Effect Correction Tailored for 18F-FDG-PET Oncological Studies
We have developed, optimized, and validated a method for partial volume effect (PVE) correction of oncological lesions in positron emission tomography (PET) clinical studies, based on recovery coefficients (RC) and on PET measurements of lesion-to-background ratio (L/B m) and of lesion metabolic volume. An operator-independent technique, based on an optimised threshold of the maximum lesion upt...
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Accurate quantification of tracer uptake in small tumors using PET is hampered by the partial-volume effect as well as by the method of volume-of-interest (VOI) delineation. This study aimed to investigate the effect of partial-volume correction (PVC) combined with several VOI methods on the accuracy and precision of quantitative PET. METHODS Four image-based PVC methods and resolution modeli...
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UNLABELLED BACKGROUND As is well known, limited spatial resolution leads to partial volume effects (PVE) and consequently to limited signal recovery. Determination of the mean activity concentration of a target structure is thus compromised even at target sizes much larger than the reconstructed spatial resolution. This leads to serious size-dependent underestimates of true signal intensity ...
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The partial volume effect in Positron Emission Tomography (PET) is a problem for quantitative radiotracer studies. This effect results from the limited spatial resolution of the imaging device (a few mm’s). Two factors are involved; the spillover of radioactivity into neighbouring regions and the underlying tissue inhomogeneity of the particular region. Linear methods are currently used to corr...
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In this thesis, a two-dimensional pixel-wise deconvolution method for partial volume correction (PVC) for combined Positron Emission Tomography and Computer Tomography (PET/CT) imaging has been developed. The method is based on Van Cittert's deconvolution algorithm and includes a noise reduction method based on adaptive smoothing and median filters. Furthermore, a technique to take into account...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2013
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2013/780458