A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities
نویسندگان
چکیده
منابع مشابه
A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities.
Polycomb response elements (PREs) are specific cis-regulatory sequences needed for transcriptional repression of HOX and other target genes by Polycomb group (PcG) proteins. Among the many PcG proteins known in Drosophila, Pho is the only sequence-specific DNA-binding protein. To gain insight into the function of Pho, we purified Pho protein complexes from Drosophila embryos and found that Pho ...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2006
ISSN: 0890-9369
DOI: 10.1101/gad.377406