A polymorphism in the MTHFD1 gene increases a mother’s risk of having an unexplained second trimester pregnancy loss
نویسندگان
چکیده
منابع مشابه
A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss.
Low maternal folate or vitamin B12 status has been implicated in numerous pregnancy complications including spontaneous abortion. The primary aim of this study was to test a polymorphism within the trifunctional folate enzyme MTHFD1 (5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase, 10-formyltetrahydrofolate synthetase) for an association with a mother'...
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15 صفحه اولSecond trimester pregnancy loss.
Second trimester pregnancy loss is uncommon, but it should be regarded as an important event in a woman's obstetric history. Fetal abnormalities, including chromosomal problems, and maternal anatomic factors, immunologic factors, infection, and thrombophilia should be considered; however, a cause-and-effect relationship may be difficult to establish. A thorough history and physical examination ...
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ژورنال
عنوان ژورنال: MHR: Basic science of reproductive medicine
سال: 2005
ISSN: 1460-2407,1360-9947
DOI: 10.1093/molehr/gah204