A Possible Mechanism of Quinolone Resistance in Vibrio anguillarum
نویسندگان
چکیده
منابع مشابه
gyrA and parC associated with quinolone resistance in Vibrio anguillarum.
Vibrio anguillarum is a Gram-negative commashaped bacterium with polar flagella that is a member of the family Vibrionaceae. It is the cause of vibriosis or haemorrhagic septicaemic disease in wild and cultured marine and freshwater fish (Actis, Tolmasky & Crosa 1999; Austin & Austin 1999). Chemotherapeutic agents, including quinolones, have been widely used for the treatment of vibriosis in cu...
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This work demonstrates that Vibrio vulnificus biotype 2, serovar E, an eel pathogen able to infect humans, can become resistant to quinolone by specific mutations in gyrA (substitution of isoleucine for serine at position 83) and to some fluoroquinolones by additional mutations in parC (substitution of lysine for serine at position 85). Thus, to avoid the selection of resistant strains that are...
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Quinolones are one of the most commonly prescribed classes of antibacterials in the world and are used to treat a variety of bacterial infections in humans. Because of the wide use (and overuse) of these drugs, the number of quinolone-resistant bacterial strains has been growing steadily since the 1990s. As is the case with other antibacterial agents, the rise in quinolone resistance threatens ...
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ژورنال
عنوان ژورنال: Fish Pathology
سال: 2006
ISSN: 0388-788X,1881-7335
DOI: 10.3147/jsfp.41.73