A Rat Monoclonal Antibody That Recognizes Pro- And Active MMP-7 Indicates Polarized Expression In Vivo
نویسندگان
چکیده
منابع مشابه
A monoclonal antibody that recognizes somatic motor neurons in the mature rat nervous system.
In order to obtain markers selective for motor neurons, an in vitro immunization was carried out using a crude homogenate of embryonic rat ventral spinal cord. We have generated a monoclonal antibody, MO-1, that binds selectively to the cell bodies of somatic motor neurons in the brain stem and spinal cord of the adult rat nervous system. In a survey of both peripheral and central nervous syste...
متن کاملTransient Expression of Biologically Active Anti-rabies Virus Monoclonal Antibody in Tobacco Leaves
Background: Rabies virus is a neurotropic virus that causes fatal, but, a preventable disease in mammals. Administration of rabies immunoglobulin (RIG) is essential for the post-exposure of the prophylaxis to prevent the disease. However, replacement of polyclonal RIGs with alternative monoclonal antibodies (MAbs) that are capable of neutralizing rabies virus has been recommend...
متن کاملA monoclonal antibody that recognizes mammalian cortical granules and a 32-kilodalton protein in mouse eggs.
The fertilization-induced exocytosis of egg cortical granules (CGs) is responsible for a block to polyspermy, crucial to the viability of many species. The contents of mammalian CGs have been an elusive target for analysis because of picogram quantities of CG proteins. By using media enriched in secreted CG contents from calcium ionophore-induced eggs as an immunogen, a monoclonal antibody was ...
متن کاملA monoclonal antibody that recognizes B cells and B cell precursors in mice
The monoclonal antibody, RA3-2C2, appears to be specific for cells within the B cell lineage. This antibody does not recognize thymocytes, peripheral T cells, or nonlymphoid hematopoietic cells in the spleen or bone marrow. Nor does it recognize the pluripotent hematopoietic stem cells, the spleen colony-forming unit, All sIg+ B cells and most plasma cells are RA3-2C2+. In addition, approximate...
متن کاملIsolation and characterization of a monoclonal antibody that recognizes the human c-kit receptor.
Stem cell factor (SCF) stimulates the growth of burst-forming unit-erythroid (BFU-E) and colony-forming unit granulocyte-macrophage (CFU-GM) by binding to a specific cell surface receptor. The receptor for SCF is encoded by the protooncogene c-kit. After immunizing mice with the human erythroleukemia cell line OCIM1, we obtained a monoclonal antibody (MoAb) that recognizes the human c-kit recep...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Hybridoma
سال: 2007
ISSN: 1554-0014,1557-8348
DOI: 10.1089/hyb.2006.028