A Reaction-Diffusion Model of ROS-Induced ROS Release in a Mitochondrial Network
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چکیده
منابع مشابه
A Reaction-Diffusion Model of ROS-Induced ROS Release in a Mitochondrial Network
Loss of mitochondrial function is a fundamental determinant of cell injury and death. In heart cells under metabolic stress, we have previously described how the abrupt collapse or oscillation of the mitochondrial energy state is synchronized across the mitochondrial network by local interactions dependent upon reactive oxygen species (ROS). Here, we develop a mathematical model of ROS-induced ...
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2010
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1000657