A Simple, General Result for the Variance of Substitution Number in Molecular Evolution

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A Simple, General Result for the Variance of Substitution Number in Molecular Evolution

The number of substitutions (of nucleotides, amino acids, etc.) that take place during the evolution of a sequence is a stochastic variable of fundamental importance in the field of molecular evolution. Although the mean number of substitutions during molecular evolution of a sequence can be estimated for a given substitution model, no simple solution exists for the variance of this random vari...

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ژورنال

عنوان ژورنال: Molecular Biology and Evolution

سال: 2016

ISSN: 0737-4038,1537-1719

DOI: 10.1093/molbev/msw063