A Time-Resolved Fluorescence Resonance Energy Transfer Assay for High-Throughput Screening of 14-3-3 Protein–Protein Interaction Inhibitors
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چکیده
منابع مشابه
Fluorescence resonance energy transfer assay for high-throughput screening of ADAMTS1 inhibitors.
A disintegrin and metalloprotease with thrombospondin type I motifs-1 (ADAMTS1) plays a crucial role in inflammatory joint diseases and its inhibitors are potential candidates for anti-arthritis drugs. For the purposes of drug discovery, we reported the development and validation of fluorescence resonance energy transfer (FRET) assay for high-throughput screening (HTS) of the ADAMTS1 inhibitors...
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ژورنال
عنوان ژورنال: ASSAY and Drug Development Technologies
سال: 2013
ISSN: 1540-658X,1557-8127
DOI: 10.1089/adt.2013.507