A two-component system gene SACE_0101 regulates copper homeostasis in Saccharopolyspora erythraea
نویسندگان
چکیده
منابع مشابه
Bacteriophages of Saccharopolyspora erythraea.
Five bacteriophages infecting only Saccharopolyspora erythraea (formerly Streptomyces erythreus) among 43 Streptomyces spp. tested were classified into two groups by phage-host relationships, restriction enzyme mapping, cohesive-end determinations, and Southern hybridizations. phi SE6, the most frequently isolated phage, produced clear plaques on all hosts tested, while phi SE45, phi SE57, phi ...
متن کاملOrganization of a cluster of erythromycin genes in Saccharopolyspora erythraea.
We used a series of gene disruptions and gene replacements to mutagenically characterize 30 kilobases of DNA in the erythromycin resistance gene (ermE) region of the Saccharopolyspora erythraea chromosome. Five previously undiscovered loci involved in the biosynthesis of erythromycin were found, eryBI, eryBII, eryCI, eryCII, and eryH; and three known loci, eryAI, eryG, and ermE, were further ch...
متن کاملDisruption of a rhodaneselike gene results in cysteine auxotrophy in Saccharopolyspora erythraea.
A 3,373-base-pair DNA segment from a clone fortuitously isolated from Saccharopolyspora erythraea by hybridization to an oligodeoxynucleotide probe was sequenced. Computer-assisted analysis of the nucleotide sequence reveals three closely linked Streptomyces open reading frames plus a fourth converging on the others. The deduced product of one of them, ORF2, shows considerable similarity to bov...
متن کاملGenome Sequence of Saccharopolyspora erythraea D, a Hyperproducer of Erythromycin
Saccharopolyspora erythraea is a Gram-positive bacterium that can produce antibiotics. However, this microorganism must often be genetically improved for higher production before it can be used in an industrial setting. Here, we report the whole-genome sequence of the industrial hyperproducer strong mutator Saccharopolyspora erythraea strain D.
متن کاملSynthesis of Erythrochelin: A Hydroxamate-Type Siderophore from Saccharopolyspora erythraea
Abstract Erythrochelin, a hydroxamate-type siderophore produced by Saccharopolyspora erythraea, is synthesized for the first time. A key building block of erythrochelin containing the 2,5-diketopiperazine ring is prepared by intramolecular cyclization of the corresponding dipeptide precursor derived from two kinds of protected δ-N-hydroxy-L-ornithines. Consecutive condensation of the building b...
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ژورنال
عنوان ژورنال: Bioresources and Bioprocessing
سال: 2020
ISSN: 2197-4365
DOI: 10.1186/s40643-020-0299-8