A305 ERYTHROMYCIN AND RELATED MACROLIDES FOR GASTROPARESIS
نویسندگان
چکیده
منابع مشابه
Differential modulation of cytokine production by macrolides: interleukin-6 production is increased by spiramycin and erythromycin.
Antibiotics do not act alone but act in conjunction with the host defense system. In particular, it has been shown that some antibiotics can modify cytokine production. We compared the in vitro effects of three macrolides (roxithromycin, spiramycin, and erythromycin) actively concentrated by leukocytes on interleukin-1 alpha, (IL-1 alpha), IL-1 beta, IL-6, and tumor necrosis factor alpha produc...
متن کاملMarine cytotoxic macrolides haterumalides and biselides, and related natural products.
Marine animals and plants are rich sources of bioactive natural products. Haterumalides and biselides, isolated from Okinawan marine animals, are 14-membered macrolides with strong cytotoxicity against human cancer cell lines. This review highlights the isolation, structures, bioactivities, and total synthesis of haterumalides, biselides, and related natural products.
متن کاملResistance to macrolides and related antibiotics in Streptococcus pneumoniae.
Resistance to erythromycin in Streptococcus pneumoniae was first detected in 1967 in the United States and subsequently worldwide (11, 20). The corresponding mechanism was rapidly identified as ribosomal methylation, which had been primarily reported as being responsible for erythromycin resistance in staphylococci (44). Further spread of resistance was then noted in a few countries, such as Fr...
متن کاملIntravenous erythromycin dramatically accelerates gastric emptying in gastroparesis diabeticorum and normals and abolishes the emptying discrimination between solids and liquids.
Erythromycin, a macrolide antibiotic, has recently been shown to have a motilin like effect on gastrointestinal muscle strips. In this study, we have evaluated the effect of erythromycin on patients with delayed gastric emptying and healthy subjects using the dual radionuclide technique. Twelve patients with gastroparesis diabeticorum and ten healthy age- and sex-matched controls were studied. ...
متن کاملNew Approaches for Gastroparesis
atients commonly present to their primary care physician with nausea and vomiting. In this setting, the challenge is to correctly diagnose the cause of the patient’s complaints and provide symptomatic relief. Although relatively uncommon compared with other conditions causing nausea and vomiting, such as gastroenteritis, bowel obstruction, and medication side effects, gastroparesis should be co...
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ژورنال
عنوان ژورنال: Journal of the Canadian Association of Gastroenterology
سال: 2018
ISSN: 2515-2084,2515-2092
DOI: 10.1093/jcag/gwy009.305