Ablynx Makes Nanobodies from Llama Bodies
نویسندگان
چکیده
منابع مشابه
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Sera of camelids contain both conventional heterotetrameric antibodies and unique functional heavy (H)-chain antibodies (HCAbs). The H chain of these homodimeric antibodies consists of one antigen-binding domain, the VHH, and two constant domains. HCAbs fail to incorporate light (L) chains owing to the deletion of the first constant domain and a reshaped surface at the VHH side, which normally ...
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ژورنال
عنوان ژورنال: Chemistry & Biology
سال: 2006
ISSN: 1074-5521
DOI: 10.1016/j.chembiol.2006.12.003