Abnormal early brain development in autism
نویسندگان
چکیده
منابع مشابه
Mapping Early Brain Development in Autism
Although the neurobiology of autism has been studied for more than two decades, the majority of these studies have examined brain structure 10, 20, or more years after the onset of clinical symptoms. The pathological biology that causes autism remains unknown, but its signature is likely to be most evident during the first years of life when clinical symptoms are emerging. This review highlight...
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Genetic studies are refining our understanding of neurodevelopmental mechanisms in autism. Some autism-related mutations appear to disrupt genes regulated by neuronal activity, which are especially important in development of the postnatal nervous system. Gene replacement studies in mice indicate that the developmental window to ameliorate symptoms may be wider than previously anticipated.
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Matthew K. Belmonte,1 Greg Allen,2 Andrea Beckel-Mitchener,3 Lisa M. Boulanger,4 Ruth A. Carper,5 and Sara J. Webb6 1Autism Research Centre, Departments of Psychiatry and Experimental Psychology, University of Cambridge, Cambridge CB2 2AH, United Kingdom, 2Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8846, 3The Beckman Institute, University of I...
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Autism is a developmental disorder defined by the presence of a triad of communication, social and stereo typical behavioral characteristics with onset before 3years of age. In spite of the fact that there are potential environmental factors for autistic behavior, the dysfunction of serotonin during early development of the brain could be playing a role in this prevalence rise. Serotonin can mo...
متن کاملEarly Brain Development
Media coverage of early brain development not only has focused public attention on early childhood but also has contributed to misunderstanding of developmental neuroscience research. This article critically summarizes current research in developmental neuroscience that is pertinent to the central claims of media accounts of early brain development, including (a) scientific understanding of for...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 2002
ISSN: 1359-4184,1476-5578
DOI: 10.1038/sj.mp.4001169