Abnormal regional homogeneity and its relationship with symptom severity in cervical dystonia: a rest state fMRI study

Abstract Background Although several brain networks play important roles in cervical dystonia (CD) patients, regional homogeneity (ReHo) changes CD patients have not been clarified. We investigated to explore ReHo at rest and analyzed its correlations with symptom severity as measured by Tsui scale. Methods A total of 19 21 gender-, age-, education-matched healthy controls underwent fMRI scans state. Data were method. Results Patients showed increased the right cerebellum crus I decreased superior medial prefrontal cortex (MPFC). Moreover, precentral gyrus, insula, bilateral middle cingulate gyrus also values. significantly positive correlation was observed between value ( p < 0.05). Conclusions Our investigation suggested abnormal existed regions “pain matrix” salience network (the insula gyrus), motor MPFC further highlighted significance these pathology CD.