Absence of somatic mutations within the Runt domain of AML2/RUNX3 in acute myeloid leukaemia
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چکیده
منابع مشابه
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Absence of Bruton's tyrosine kinase (Btk) mutations in patients with acute myeloid leukaemia.
Bruton's tyrosine kinase (Btk) is a non-receptor protein tyrosine kinase (PTK) that is expressed in all haemopoietic lineages except mature T cells and plasma cells. Despite the broad range of expression. mutations that inactivate this molecule affect primarily the development of the B-cell lineage. As a PTK, Btk could potentially be involved directly or indirectly in the processes that relate ...
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ژورنال
عنوان ژورنال: Leukemia
سال: 2003
ISSN: 0887-6924,1476-5551
DOI: 10.1038/sj.leu.2403007