Acidic and basic fibroblast growth factors involved in cardiac angiogenesis following infarction
نویسندگان
چکیده
منابع مشابه
Acidic and basic fibroblast growth factors are present in glioblastoma multiforme.
Immunohistochemistry was performed on paraffin sections from human glioblastoma multiforme and normal brain tissue. Acidic fibroblast growth factor (FGF) was abundantly present in astrocytes from all glioblastomas studied. Basic FGF was found in the matrix surrounding proliferating blood vessels in most of the glioblastomas. In contrast, astrocytes from normal brain did not contain acidic FGF, ...
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BACKGROUND We used biochemical and immunohistochemical techniques to investigate the expression and distribution of immunoreactive basic and acidic fibroblast growth factors (bFGF and aFGF, respectively) in the hearts of rat embryos (11-20 days of gestation) and of postnatal rats (1-35 days after birth). Our purpose was to assess the relation between the cellular distribution of these growth fa...
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Basic fibroblast growth factor (bFGF) supports the survival of neurons from many regions of the E18 fetal rat brain. Survival was significantly increased for neurons derived from the hippocampus, entorhinal cortex (EC), frontal cortex, parietal cortex (PC), occipital cortex, striatum, septum, and thalamus, but not from the subiculum (Sb). The proportion of neurons rescued by bFGF varied among b...
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Fibroblast growth factors (FGFs) are potent mitogens for several cell types, including endothelial cells. cDNA clones encoding receptors for members of the FGFs family have recently been reported (1, 2, 3). However, only a partial sequence has been published so far encoding a human receptor for acidic and basic FGF (4, 5), which was named flg. Using oligonucleotide probes derived from the flg s...
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The aim of the present study was to evaluate the effect of astragalosides (ASTs) on angiogenesis, as well as the expression of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) following myocardial infarction (MI). MI was induced in rats by ligation of the left coronary artery. Twenty‑four hours after surgery, the rats were divided into low‑dose, high‑dose, con...
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ژورنال
عنوان ژورنال: International Journal of Cardiology
سال: 2011
ISSN: 0167-5273
DOI: 10.1016/j.ijcard.2010.07.024