Action Potential Timing Precision in Dorsal Cochlear Nucleus Pyramidal Cells

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Action potential timing precision in dorsal cochlear nucleus pyramidal cells.

Many studies of the dorsal cochlear nucleus (DCN) have focused on the representation of acoustic stimuli in terms of average firing rate. However, recent studies have emphasized the role of spike timing in information encoding. We sought to ascertain whether DCN pyramidal cells might employ similar strategies and to what extent intrinsic excitability regulates spike timing. Gaussian distributed...

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Street and Manis Action potential timing precision in dorsal cochlear nucleus pyramidal cells

Many studies of the dorsal cochlear nucleus (DCN) have focused on the representation of acoustic stimuli in terms of average firing rate. However, recent studies have emphasized the role of spike timing in information encoding. We sought to ascertain whether DCN pyramidal cells might employ similar strategies and to what extent intrinsic excitability regulates spike timing. Gaussian distributed...

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A Simulation-Based Study of Dorsal Cochlear Nucleus Pyramidal Cell Firing Patterns

A two-variable integrate and fire model is presented to study the role of transient outward potassium currents in producing temporal aspects of dorsal cochlear nucleus (DCN) pyramidal cells with different profiles namely the chopper, the pauser and the buildup. This conductance based model is a reduced version of KM-LIF model (Meng & Rinzel, 2010) which captures qualitative firing features of a...

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Dendritic Ca2+ transients evoked by action potentials in rat dorsal cochlear nucleus pyramidal and cartwheel neurons.

Simultaneous fluorescence imaging and electrophysiologic recordings were used to investigate the Ca(2+) influx initiated by action potentials (APs) into dorsal cochlear nucleus (DCN) pyramidal cell (PC) and cartwheel cell (CWC) dendrites. Local application of Cd(2+) blocked Ca(2+) transients in PC and CWC dendrites, demonstrating that the Ca(2+) influx was initiated by dendritic Ca(2+) channels...

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a simulation-based study of dorsal cochlear nucleus pyramidal cell firing patterns

a two-variable integrate and fire model is presented to study the role of transient outward potassium currents in producing temporal aspects of dorsal cochlear nucleus (dcn) pyramidal cells with different profiles namely the chopper, the pauser and the buildup. this conductance based model is a reduced version of km-lif model (meng & rinzel, 2010) which captures qualitative firing features of a...

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ژورنال

عنوان ژورنال: Journal of Neurophysiology

سال: 2007

ISSN: 0022-3077,1522-1598

DOI: 10.1152/jn.00469.2006