Active nanoceramic compound dipped in biopolymers to create composite coating for metallic implant surface

Biofunctionalization of an implant using functional ceramics with exceptional electrical characterization, such as BaTiO3 and SrTiO3, has gained considerable attention in creating a composite coating bio-polymer to activate metal surfaces for bone tissue engineering applications and, at the same time, resist bacterial infection. A Ti–Zr alloy sample was created by powder technology, then applied electrospinning technique. Individually, nanopowders ceramic compounds nBaTiO3 nSrTiO3 were added blend polycaprolactone chitosan create solutions that could be converted into nanofibrous layer The samples analyzed their morphology, chemical composition, surface roughness, dielectric constant, wettability. techniques employed SEM, EDS, FTIR, LCR meter, contact angle goniometer. samples' cytocompatibility assessed examining cell viability, ALP activity, proliferation, attachment MC3T3-E1 osteoblast cells on both coated uncoated surfaces.The resistance assays conducted against Staphylococcus aureus Streptococcus mutans. findings demonstrate notable enhancement biocompatibility specimens following week cellular cultivation. containing piezoelectric constant Ɛr (16) close dry human 100HZ frequency. Cell proliferation increases dramatically time samples, improvement approaches 125.16% (BA1) 111.38% (SR1) compared Ti–25Zr sample. viability percentage is bare Ti–25Zr, which 80.52 ± 1.97% crucial increase, while 181.63 17.87 170.09 18.12%. No zone inhibition detected test sample, show adequate comparable inhibitory zone. nano-fiber strong biocompatibility, process simple economical, holding potential use orthodontic orthopedic regeneration applications.