Acute angle-closure glaucoma following botulinum toxin injection for blepharospasm.

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Acute angle-closure glaucoma following botulinum toxin injection for blepharospasm.

Botulinum toxin inhibits acetylcholine release and therefore could cause mydriasis. We report a case of acute angle-closure glaucoma which occurred shortly after a series of injections of botulinum toxin round the eyelids for blepharospasm.

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A 50-year-old female presented with bilateral retinitis pigmentosa (RP) and acute angle closure (AAC) with fixed mid-dilated pupil and high intraocular pressure (IOP) in the left eye following left side periorbital botulinum toxin A injection for blepharospasm. Glaucomatous optic neuropathy and retinal nerve fiber layer defect were observed in the affected eye using optical coherence tomography...

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This is a case report describing recurrent intermittent acute angle closure episodes in the setting of topiramate use in a female suffering from migraines. Despite laser peripheral iridotomy placement for the pupillary block component, and the discontinuation of topiramate, the acute angle closure did not resolve in the left eye with chronic angle closure and the patient required urgent trabecu...

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Botulinum toxin (BT) is a polypeptidic neurotoxin produced by Clostridium botulinum that is widely used in medicine [1]. The U.S. Food and Drug Administration (FDA) approved BT type A injection use for the treatment of cervical dystonia, blepharospasm, primary axillary hyperhydrosis and cosmetic use for glabellar lines, and it is also widely used to treat spasticity, siallorhea, chronic tension...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1990

ISSN: 0007-1161

DOI: 10.1136/bjo.74.5.309