Acute ethanol exposure inhibits silencing of cerebellar Golgi cell firing induced by granule cell axon input
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چکیده
منابع مشابه
Acute ethanol exposure inhibits silencing of cerebellar Golgi cell firing induced by granule cell axon input
Golgi cells (GoCs) are specialized interneurons that provide inhibitory input to granule cells in the cerebellar cortex. GoCs are pacemaker neurons that spontaneously fire action potentials, triggering spontaneous inhibitory postsynaptic currents in granule cells and also contributing to the generation tonic GABAA receptor-mediated currents in granule cells. In turn, granule cell axons provide ...
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The function of inhibitory interneurons within brain microcircuits depends critically on the nature and properties of their excitatory synaptic drive. Golgi cells (GoCs) of the cerebellum inhibit cerebellar granule cells (GrCs) and are driven both by feedforward mossy fiber (mf) and feedback GrC excitation. Here, we have characterized GrC inputs to GoCs in rats and mice. We show that, during su...
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ژورنال
عنوان ژورنال: Frontiers in Integrative Neuroscience
سال: 2014
ISSN: 1662-5145
DOI: 10.3389/fnint.2014.00010