Adaptive support ventilation as an acceptable mode to prevent airflow limitation, air entrapment, dynamic hyperinflation and patient-ventilator dyssynchrony

Adaptive support ventilation as an acceptable mode to prevent airflow limitation, air entrapment, dynamic hyperinflation and patient-ventilator dyssynchrony

Introduction Adaptive support ventilation (ASV) is a dual control mode, using measured dynamic compliance and time constant, with an automated adjustment of tidal volume and respiratory rate combined to meet the preset minute ventilation. The purpose of this study was to evaluate the effectiveness of (ASV) in restoring air flow stability, decrease work of breathing and improving dyssynchrony in...

Effects of PEEP on dynamic hyperinflation in patients with airflow limitation.

We have studied the effects of extrinsically applied PEEP (PEEPe) and intrinsic PEEP (PEEPi) on lung volume and peak airway pressure (Paw,peak) in 10 patients with airflow limitation during mechanical ventilation. PEEPe was applied in 2-4 cm H2O increments until values greater than PEEPi were reached. Total lung hyperinflation was quantified by measuring the expired volume resulting from deflat...

Adaptive Support Ventilation as the sole mode of ventilatory support in chronically ventilated patients.

OBJECTIVE To describe the outcome of patients admitted to a new private facility for chronically ventilated patients in the Ashdod area of Israel. METHODS On arrival, all patients were placed on Adaptive Support Ventilation (ASV) at 90% of target minute ventilation for lean body weight, reducing progressively in weekly decrements of 10% down to 60% of target minute ventilation if adequate spo...

Ventilation heterogeneity in ex-smokers without airflow limitation.

RATIONALE AND OBJECTIVES Hyperpolarized (3)He magnetic resonance imaging (MRI) ventilation abnormalities are visible in ex-smokers without airflow limitation, but the clinical relevance of this is not well-understood. Our objective was to phenotype healthy ex-smokers with normal and abnormally elevated ventilation defect percent (VDP). MATERIALS AND METHODS Sixty ex-smokers without airflow li...

Practice Patient - Ventilator Dyssynchrony : Clinical Significance and Implications for