Adenocarcinoma of Unknown Primary Site

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Adenocarcinoma of Unknown Primary Site

BACKGROUND Metastatic cancer of unknown primary site occupies 0.5-10% of all diagnosed cancer patients and includes various tumors with diverse responses to systemic chemotherapy. Adenocarcinoma of unknown primary site (ACUPS), the most common subtype, has no standard treatment, rarely responds to conventional treatment and has a poor survival rate. METHODS The retrospective study was perform...

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Cancer of unknown primary site.

Copyright © 2014 Massachusetts Medical Society Cancer of unknown primary site is a heterogeneous group of cancers for which the anatomical site of origin remains occult after detailed investigations.1,2 The emergence of sophisticated imaging, immunohistochemical testing, and molecular-profiling tools has influenced our approach to unknown primary cancer, although it has also increased the ambig...

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Immunohistochemical Profile for Unknown Primary Adenocarcinoma

BACKGROUND Development of tailored treatment based on immunohistochemical profiles (IPs) of tumors for cancers of unknown primary is needed. METHODOLOGY/PRINCIPAL FINDINGS We developed an algorithm based on primary known adenocarcinoma for testing sensitivity and specificity. Formalin-fixed paraffin-embedded tissue samples from 71 patients of unfavorable subsets of unknown primary adenocarcin...

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Putative lung adenocarcinoma with epidermal growth factor receptor mutation presenting as carcinoma of unknown primary site

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[Metastatic cancer of unknown primary site].

The history, physical examination, radiographic and laboratory studies and histological diagnosis must be completely evaluated to search for the primary tumor. For diagnosis of cervical lymph node metastasis, not only whole body examination but also head and neck examination is important in which quadrascopy (nasopharyngeal, laryngeal and esophageal fiberoscopy and bronchoscopy) must be perform...

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ژورنال

عنوان ژورنال: The Korean Journal of Internal Medicine

سال: 2002

ISSN: 1226-3303,2005-6648

DOI: 10.3904/kjim.2002.17.4.234