Adrenal computed tomography and NP-59 usefulness for diagnosing aldosterone-producing adenomas and idiopathic hyperaldosteronism in primary hyperaldosteronism

Plasma immunoreactive gamma melanotropin in patients with idiopathic hyperaldosteronism, aldosterone-producing adenomas, and essential hypertension.

A non-ACTH aldosterone-stimulating factor(s) has been implicated in the pathogenesis of idiopathic hyperaldosteronism (IHA). Although this factor has not been fully characterized, some evidence suggests that it may be related to a pro-gamma-melanotropin (pro-gamma-MSH), derived from the NH2-terminal region of pro-opiomelanocortin. In the present study, plasma immunoreactive (IR-) gamma-MSH leve...

Adrenal Venous Sampling in Primary Hyperaldosteronism

Adrenal venous sampling (AVS) is used to distinguish unilateral from bilateral aldosterone hypersecretion as a cause of primary hyperaldosteronism (PHA). This distinction is critical because unilateral disease is treated, and often cured, by adrenalectomy, whereas bilateral hypersecretion should be managed medically. In this article, we review the epidemiology and etiologies of PHA, present scr...

[Primary hyperaldosteronism due to adrenal adenoma].

Hyperaldosteronism from adrenal carcinoma.

criteria for a diagnosis of infectious mononucleosis. In a more recent report of an outbreak of the disease Dunnet (1963) described 80 cases; the diagnostic criteria used were stringent. Though almost all of the 80 cases had evidence of hepatic involvement and 13 (16%) had electrocardiographic changes, only a few had the radiological appearances of enlarged hilar lymph nodes and none had pulmon...

Giant adrenal adenoma with hyperaldosteronism.

1. Adrenal tumor. (A) Abdominal computed tomography showed a large mass with smooth margin, 6.0 cm in diameter, in the left adrenal gland. No sweling of the lymph nodes around the tumor was observed. (B) An adenoma measuring 7.5×6.0×5.5 cm and weighing 122 g with a smooth surface was removed. Its cut surface was golden yelow. (C) HE stain ×20. The adenoma was encapsulated. The adjacent normal a...