Age-related decline in cognitive flexibility in female chimpanzees

Neuroanatomical substrates of age-related cognitive decline.

There are many reports of relations between age and cognitive variables and of relations between age and variables representing different aspects of brain structure and a few reports of relations between brain structure variables and cognitive variables. These findings have sometimes led to inferences that the age-related brain changes cause the age-related cognitive changes. Although this conc...

When does age-related cognitive decline begin?

Cross-sectional comparisons have consistently revealed that increased age is associated with lower levels of cognitive performance, even in the range from 18 to 60 years of age. However, the validity of cross-sectional comparisons of cognitive functioning in young and middle-aged adults has been questioned because of the discrepant age trends found in longitudinal and cross-sectional analyses. ...

Network signatures of age-related cognitive decline.

Genetic Biomarkers on Age-Related Cognitive Decline

With ever-increasing elder populations, age-related cognitive decline, which is characterized as a gradual decline in cognitive capacity in the aging process, has turned out to be a mammoth public health concern. Since genetic information has become increasingly important to explore the biological mechanisms of cognitive decline, the search for genetic biomarkers of cognitive aging has received...

Is Age-Related Decline in Female Fertility A Mitochondrial Dysfunction?

In humans, the fertility in female declines slowly from the age of 30 years [1,2]. Embryo implanting ability and survival start declining gradually after 30 years of age, but by more than two thirds after 40 years and in younger women with reduced ovarian reserve [3]. While decline in the frequency of intercourse is one of the reasons, reduction in the quality of either the embryos arising from...