Agrin is required for survival and function of monocytic cells
نویسندگان
چکیده
منابع مشابه
Dicer is required for Sertoli cell function and survival.
Dicer is a key enzyme that processes microRNA precursors into their mature form, enabling them to regulate gene expression. Dicer null mutants die before gastrulation. To study Dicer function in testis development, we crossed mice carrying a conditional Dicer allele with an AMH-Cre transgenic line, thereby inactivating Dicer in Sertoli cells around embryonic day 14.0 (E14.0). Dicer null Sertoli...
متن کاملTRPM8 is required for survival and radioresistance of glioblastoma cells
TRPM8 is a Ca2+-permeable nonselective cation channel belonging to the melastatin sub-group of the transient receptor potential (TRP) family. TRPM8 is aberrantly overexpressed in a variety of tumor entities including glioblastoma multiforme where it reportedly contributes to tumor invasion. The present study aimed to disclose further functions of TRPM8 in glioma biology in particular upon cell ...
متن کاملSox4 is required for the survival of pro-B cells.
The development of mature B cells from hematopoietic stem cells is a strictly orchestrated process involving multiple regulatory genes. The transcription factor Sox4 is required for this process, but its role has not been systematically studied, and the underlying mechanisms remain unknown. To determine when and how Sox4 functions in the stepwise process of B cell development, we used mice harb...
متن کاملThe Effects of Lithium Chloride on Survival and Function of in Vitro Cultured Human Granulosa Cells
Purpose: To investigate the effect of lithium chloride (LiCl) on survival and functional activity of in vitro cultured human granulosa cells (GCs). Materials and Methods: GCs were isolated from follicular fluid of women undergoing IVF/ICSI. After RBCs removal, GCs were plated in a medium containing varying concentrations of LiCl including 1, 2 and 5mM for two weeks period. A culture without Li...
متن کاملHow Much Time is Required for the Process of Reviewing and Publishing an Article?
از زمانی که پژوهش‌گران نگارش یک مقاله را به پایان برده و ارسال آن به مجله را در دستور کار خویش قرار می‌دهند، یکی از مهم‌ترین سؤالاتی که ممکن است ذهن آن‌ها را مشغول نماید این است که: " در مجله مورد نظر، چقدر زمان برای فرآیند بررسی و چاپ یک مقاله مورد نیاز است؟" این سوال، به خصوص برای دانشجویان تحصیلات تکمیلی که برای چاپ مقاله خود عجله دارند، از اهمیت بیش‌تری برخوردار است. توصیه شخصی من این است...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood
سال: 2012
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2011-09-382812