AH-DB: collecting protein structure pairs before and after binding

AH-DB: collecting protein structure pairs before and after binding

This work presents the Apo-Holo DataBase (AH-DB, http://ahdb.ee.ncku.edu.tw/ and http://ahdb.csbb.ntu.edu.tw/), which provides corresponding pairs of protein structures before and after binding. Conformational transitions are commonly observed in various protein interactions that are involved in important biological functions. For example, copper-zinc superoxide dismutase (SOD1), which destroys...

P-11: Evaluation of Heat Shock Protein A2 in Male Rats before and after Varicocele Induction

Background: Varicocele is a major cause of male infertility, as it may impair spermatogenesis through several distinct pathophysiological mechanisms including hypoxia, renal-adrenal reflux, hormonal dysfunction, autoimmunity, oxidative stress and hyperthermia. HSP70s are members of the heat shock protein (HSP) family, which are considered intracellular chaperones. Their expressions can increase...

Structure of the elongating ribosome: Arrangement of the two tRNAs before and after translocation (protein synthesisyneutron scatteringytRNA binding sites)

The ribosome uses tRNAs to translate the genetic information into the amino acid sequence of proteins. The mass ratio of a tRNA to the ribosome is in the order of 1:100; because of this unfavorable value it was not possible until now to determine the location of tRNAs within the ribosome by neutron-scattering techniques. However, the new technique of proton-spin contrast-variation improves the ...

Efficient Discovery of Binding Motif Pairs from Protein–protein Interactions

"Physical properties and electronic structure of LaNi5 compound before and after hydrogenation: An experimental and theoretical approach"

The present study deals with the experimental and theoretical approaches of LaNi5 hydrogen storage alloy. The structural, morphological and hydrogenation characterization of this sample which is synthesized by the arc melting technique were carried out by X-ray diffraction, scanning electron microscopy and a homemade Sievert's type apparatus, respectively. The results showed that after several ...