Alloimmunization to the D antigen by a patient with weak D type 21
نویسندگان
چکیده
منابع مشابه
Novel weak D types 31 and 32: adsorption-elution-supported D antigen analysis and comparison to prevalent weak D types.
BACKGROUND Weak D types are thought to express rather quantitative than qualitative D antigen variants. Distinct type-specific phenotypes and weak D cases with anti-D alloimmunization, however, suggest a variable degree of D antigen alteration. STUDY DESIGN AND METHODS Variant D types were investigated by use of molecular typing, RHD sequencing, extended serologic D antigen investigations, an...
متن کاملPrimary Anti-D Alloimmunization Induced by "Asian Type" RHD (c.1227G>A) DEL Red Cell Transfusion
Hyung-Seok Yang, M.D., Min Young Lee, M.D., Tae Sung Park, M.D., Sun Young Cho, M.D., Hee Joo Lee, M.D., Gayoung Lim, M.D., Dae Dong Lee, M.D., Seung Hwan Oh, M.D., Duck Cho, M.D., and Kyoung Un Park, M.D. Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Seoul; Blood Laboratory Center, Central, Korean Red Cross, Seoul; Blood Laboratory Center, Nambu, Korean Red Cross...
متن کاملLow frequency of anti-D alloimmunization following D+ platelet transfusion: the Anti-D Alloimmunization after D-incompatible Platelet Transfusions (ADAPT) study.
The reported frequency of D alloimmunization in D- recipients after transfusion of D+ platelets varies. This study was designed to determine the frequency of D alloimmunization, previously reported to be an average of 5 ± 2%. A primary anti-D immune response was defined as the detection of anti-D ≥ 28 d following the first D+ platelet transfusion. Data were collected on 485 D- recipients of D+ ...
متن کاملRHD*weak D type 38: a family study
he RHD gene is responsible for the expression of the D antigen hile RHCE encodes proteins carrying antigens C or c, and E r e. RHD is present or absent depending on the RH haplotype, nd RHCE displays four common alleles (ce, Ce, cE, CE) responible for the expression of the two antithetical (allelic) series f antigens. RHD gene deletion is the leading cause of the Dhenotype worldwide.1 Functiona...
متن کاملA rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child
We are reporting a rare case of hemolytic disease of newborn with weak D antigen in child. A 3rd order male child of G3P3A0 mother was admitted at 8th h of life with jaundice. Blood group of both mother and child were A Rh D negative. Baby's direct coombs test was positive. Weak D antigen was positive in baby. Hematological parameters showed all the signs of ongoing hemolysis, and the bilirubin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Immunohematology
سال: 2020
ISSN: 0894-203X,1930-3955
DOI: 10.21307/immunohematology-2019-197