Among respiratory symptoms, wheeze associates most strongly with impaired lung function in adults with asthma - A long-term prospective cohort study

Background: Asthma is a common disease and major public health concern. Respiratory symptoms are related to its prognosis, which in turn associates with lung function. Still this association on long-term basis not entirely understood. Aim: To study the of type number respiratory FEV1 decline women men asthma. Method: A population-based cohort adults asthma was examined at entry between 1986 2001 follow-up 2012-2014, n=977 had valid measurements both occasions. Data regarding (recurrent wheeze, dyspnea, longstanding cough productive cough) were analyzed relation annual FEV1, unadjusted adjusted for other potentially associated factors by linear regression. Results: For sexes recurrent wheeze dyspnea lower follow-up, while only follow-up. No associations found FEV1. In analyses, remained significant among women. Also, higher present after adjustment. Conclusions: Particularly may predict function also long run