An adaptive Expectation–Maximization algorithm with GPU implementation for electron cryomicroscopy
نویسندگان
چکیده
منابع مشابه
An adaptive Expectation-Maximization algorithm with GPU implementation for electron cryomicroscopy.
Maximum-likelihood (ML) estimation has very desirable properties for reconstructing 3D volumes from noisy cryo-EM images of single macromolecular particles. Current implementations of ML estimation make use of the Expectation-Maximization (EM) algorithm or its variants. However, the EM algorithm is notoriously computation-intensive, as it involves integrals over all orientations and positions f...
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ژورنال
عنوان ژورنال: Journal of Structural Biology
سال: 2010
ISSN: 1047-8477
DOI: 10.1016/j.jsb.2010.06.004