An adjoint method for channel localization
نویسندگان
چکیده
منابع مشابه
An adjoint method for channel localization.
Single cells learn by tuning their synaptic conductances and redistributing their excitable machinery. To reveal its learning rules, one must therefore know how the cell remaps its ion channels in response to physiological stimuli. We here develop an adjoint approach for discerning the non-uniform distribution of a given channel type from knowledge of the time course of membrane potential at tw...
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ژورنال
عنوان ژورنال: Mathematical Medicine and Biology: A Journal of the IMA
سال: 2006
ISSN: 1477-8602,1477-8599
DOI: 10.1093/imammb/dql004