An Advanced ‘clickECM’ That Can be Modified by the Inverse‐Electron‐Demand Diels‐Alder Reaction
نویسندگان
چکیده
The extracellular matrix (ECM) is a promising biomaterial for numerous applications. Using cells from human donors and synthetic carbohydrate derivatives, functionalized ECM modified with dienophiles, such as cyclopropenes, was produced by metabolic glycoengineering. cover feature highlights the application of inverse-electron-demand Diels-Alder reaction to “click” variable groups R in cell-friendly manner. In this way, can be equipped new biological or chemical functions, which opens wide range future (Image created BioRender.com.) More information found Full Paper V. Wittmann, P. J. Kluger et al.
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ژورنال
عنوان ژورنال: ChemBioChem
سال: 2021
ISSN: ['1439-7633', '1439-4227']
DOI: https://doi.org/10.1002/cbic.202100531