An entropy-based method to measure phase-locking between LFP and spikes

Phase-locking between local field potential and spikes has been widely investigated through neurophysiological analysis. Two indices most frequently adopted traditionally include the mean resultant length p of Rayleigh test. However, traditional method is found less reliable for cases with substantial sample sizes or bimodal distribution. In this article, K we propose an entropy-based to detect measure phase-locking. Simulation results prove that can be effectively applied a relatively large size it phase-locking even under conditions two peaks opposite phases. Furthermore, thresholds help intensity spike We also apply proposed our experimental data find phase locking phases, which would left out in