An Ovine Model of Hyperdynamic Endotoxemia and Vital Organ Metabolism
نویسندگان
چکیده
منابع مشابه
Vital organ blood flow during hyperdynamic sepsis.
OBJECTIVES To develop a nonlethal model of hyperdynamic sepsis, and to measure vital organ blood flows in this setting. DESIGN Randomized crossover animal study. SETTING Animal laboratory of university-affiliated physiology institute. SUBJECTS Seven Merino cross sheep. INTERVENTIONS Surgical implantation of transit-time flow probes around sagittal sinus and circumflex coronary, superior...
متن کاملBiphasic changes in left ventricular function during hyperdynamic endotoxemia.
Cardiac contractility was studied in a clinically relevant conscious swine model simulating human hemodynamics during endotoxemia. The slope of the end-systolic pressure-volume relationship [end-systolic elastance ( E ES)] was used as a load-independent contractility index. Chronic instrumentation in 10 pigs included two pairs of endocardial ultrasonic crystals for measuring internal major and ...
متن کاملThe comparative clinical efficacy of intravenous insulin regular, dexamethasone and flunixin meglumine on ovine experimental endotoxemia
The lack of an effective treatment for endotoxemia causes high mortality rates in affected animals. Forty clinically healthy 1-year old Iranian fat-tailed ewes were assigned randomly into 8 experimental equal (n = 5) groups, comprising Insln 1.5, Insln 3, Insln 6, Insln 9, Insln 20, Dexa, Flnx and Control. Lipopolysaccharide from E. coli serotype O55:B5 was used to induce endot...
متن کاملToxicity of Manganese Titanate on Rat Vital Organ Mitochondria
The TiO2, which is a main material in the field of photocatalytic reactions, includes rutile and anatase phase. Titanium dioxide has possessed notice due to its promising applications in the environmental photocatalytic degradation of pollutants of organic compound in waste water and utilization of solar energy. The nanosized manganese titanate (pyrophanite) MnTiO3 was collected by oxidation of...
متن کاملToxicity of Manganese Titanate on Rat Vital Organ Mitochondria
The TiO2, which is a main material in the field of photocatalytic reactions, includes rutile and anatase phase. Titanium dioxide has possessed notice due to its promising applications in the environmental photocatalytic degradation of pollutants of organic compound in waste water and utilization of solar energy. The nanosized manganese titanate (pyrophanite) MnTiO3 was collected by oxidation of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Shock
سال: 2018
ISSN: 1073-2322,1540-0514
DOI: 10.1097/shk.0000000000000904