Analysis of Neutrophil Lymphocyte Ratio and Absolute Lymphocyte Count as Predictors of Severity of COVID-19 Patients

It is important to predict the severity of COVID-19 during pandemic. Both Neutrophil Lymphocyte Ratio (NLR) andAbsolute Count (ALC) are two easy, low-cost, and fast inflammatory markers, which positively correlate with theseverity COVID-19. The purpose this research was analyze value NLR ALC as predictors COVID-19severity. This a retrospective study using medical record data 376 patients duringApril-September 2020 at Hasanuddin University Hospital Makassar City Regional Hospital. Patients were classifiedinto non-severe severe lymphocyte ratio values determined based on routineblood test (Sysmex XS-800i) results, statistical analysis Independent T-test, while diagnostic wereanalyzed Receiver Operating Characteristics (ROC) curve obtain cut-off value, p < 0.05 significant. Thesamples consisted 372 49 patients. in non-severe(4.02±5.22) significantly different from (9.81±7.06) (p 0.001), similar non-severe(2.00±0.83x103/μL) (1.22±0.78x103/μL) 0.001). operating characteristics showedthat had sensitivity 91.8% specificity 66.4% ≥ 3.17 Negative Predict Value (NPV) 98.2%and Positive (PPV) 29.0%; 81.6% 64.8% cut-off≤ 1.74x103/μL NPV 95.9% PPV 25.8%. Increased decreased patientsoccurred due an increased response resulting cellular immunity. operatingcharacteristics showed for 1.74x103/μL, indicating optimum andspecificity. concluded that can be used and≤ respectively.