Annotation of phenotypic diversity: decoupling data curation and ontology curation using Phenex
نویسندگان
چکیده
منابع مشابه
Annotation of phenotypic diversity: decoupling data curation and ontology curation using Phenex
BACKGROUND Phenex (http://phenex.phenoscape.org/) is a desktop application for semantically annotating the phenotypic character matrix datasets common in evolutionary biology. Since its initial publication, we have added new features that address several major bottlenecks in the efficiency of the phenotype curation process: allowing curators during the data curation phase to provisionally reque...
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BACKGROUND Phenotypic differences among species have long been systematically itemized and described by biologists in the process of investigating phylogenetic relationships and trait evolution. Traditionally, these descriptions have been expressed in natural language within the context of individual journal publications or monographs. As such, this rich store of phenotype data has been largely...
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As the amount of data being generated in biology has increased, a major challenge has been how to store and represent this data in a way that makes it easily accessible to researchers from diverse domains. Understanding the relationship between genotype and phenotype is a major focus of biological research. Various approaches to providing the link between genes and their functions have been und...
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Data quality is an issue that touches on every aspect of the research data landscape and is therefore appropriate to examine in the context of planning for future research data infrastructures. As producers, researchers want to believe that they produce high quality data; as consumers, they want to obtain data of the highest quality. Data centres typically have stringent controls to ensure that...
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Hypothetical proteins (HPs) are the proteins predicted to be expressed from an open reading frame, making a substantial fraction of proteomes in both prokaryotes and eukaryotes. Genome projects have led to the identification of many therapeutic targets, the putative function of the protein, and their interactions. In this review we enlist various methods linking annotation to structural and fun...
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ژورنال
عنوان ژورنال: Journal of Biomedical Semantics
سال: 2014
ISSN: 2041-1480
DOI: 10.1186/2041-1480-5-45