Anti-neutrophil Cytoplasmic Antibodies Tests: Which Tests Should be Used in Practice?

Anti-Cardiolipin and Anti-Neutrophil Cytoplasmic Antibodies in Iranian Patients with Behcet's Disease

Background: The prevalence of anti-Neutrophil Cytoplasmic Antibodies (ANCAs) and anti-Cardiolipin Antibodies (anti-CL Ab) in Behcet’s Disease (BD) and also their roles in vascular involvement is controversial. Objective: To assess the prevalence of ANCAs and anti-CL Ab as well as their correlations with clinical manifestations in Iranian patients with BD. Methods: In this case/control study, th...

When should tests for unexpected antibodies be done during pregnancy?

B oth the AABB’s Guidelines for Prenatal and Perinatal Immunohematology and the practice bulletin of the American College of Obstetricians and Gynecologists (ACOG) on “Management of Alloimmunization during Pregnancy” advocate testing pregnant women for unexpected antibodies to red blood cell (RBC) antigens at the first-trimester visit. This testing serves to detect those alloantibodies capable ...

Anti-neutrophil cytoplasmic antibodies and vasculitis.

[Anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitides].

The anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitides are a group of uncommon diseases characterised by inflammatory cell infiltration and necrosis of blood vessel walls. ANCA there has been considerable progress towards understanding their pathogenesis. This results in endothelial activation with increased transmigration and adherence of neutrophils to vessel walls. Specific ...

Which statistical tests should I use?

Statistical tests can be powerful tools for researchers. They provide valuable evidence from which we make decisions about the significance or robustness of research findings. Statistical tests are a critical part of the answers to our research questions and ultimately determine how confident we can be in the evidence to inform clinical practice. In addition to analysing data to answer research...