Antimalarial Activity of 2,6-Dibenzylidenecyclohexanone Derivatives
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چکیده
منابع مشابه
Synthesis and antimalarial activity of febrifugine derivatives.
The regioisomers (2a,b) of the piperidine ring of febrifugine (1a) and isofebrifugine (1b) were synthesized from 4-allyl-3-piperidone (5). Reduction of 5 afforded a mixture of the trans and cis alcohols (6a,b) without diastereoselectivity; this result differentiated it from the reduction of 2-allyl-3-piperidone (14). The antimalarial activity of 2a,b and related compounds was tested.
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ژورنال
عنوان ژورنال: Bioorganic & Medicinal Chemistry Letters
سال: 2021
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2021.128216