Antimicrobial activity of pleurocidin is retained in Plc-2, a C-terminal 12-amino acid fragment

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Antimicrobial activity of pleurocidin is retained in Plc-2, a C-terminal 12-amino acid fragment

An analysis of a series of five peptides composed of various portions of the pleurocidin (Plc) sequence identified a l2-amino acid fragment from the C-terminus of Plc, designated Plc-2, as the smallest fragment that retained a antimicrobial activity comparable to that of the parent compound. MIC tests in vitro with low-ionic-strength medium showed that Plc-2 has potent activity against Pseudomo...

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ژورنال

عنوان ژورنال: Peptides

سال: 2013

ISSN: 0196-9781

DOI: 10.1016/j.peptides.2013.03.030