Antiplasmodial activity of solvent fractions of methanolic root extract of Dodonaea angustifolia in Plasmodium berghei infected mice
نویسندگان
چکیده
منابع مشابه
Antiplasmodial activity of solvent fractions of methanolic root extract of Dodonaea angustifolia in Plasmodium berghei infected mice
BACKGROUND Malaria is one of the most important infectious diseases in the World. The choice for the treatment is highly limited, and several of these may eventually be lost or compromised due to drug resistance. The use of plant medicine in the treatment of malaria and its various presentations is a common practice in many countries of Africa where the disease is mostly endemic. Dodonaea angus...
متن کاملAntiplasmodial activity of solvent fractions of methanolic root extract of Dodonaea
Title:Antiplasmodial activity of solvent fractions of methanolic root extract of Dodonaea angustifolia in Plasmodium berghei infected mice
متن کاملIn vivo Antiplasmodial and Cytotoxic Activity of Achyranthes aspera and Ficus thoningii in Mice Infected with Plasmodium berghei
Malaria remains o n e o f the leading causes of morbidity and mortality in tropical countries, and the alarming spread of the drugs resistant malaria parasite underscores the need to develop new antimalarial compounds. In this study, the phytochemical constituents, in vivo antiplasmodial, and cytotoxic activity of methanolic extracts of Achyranthes aspera and Ficus thoningii were evaluated usin...
متن کاملAntiplasmodial Compounds from Leaves of Dodonaea angustifolia
Background Dodonaea angustifolia is used in Ethiopian traditional medicine to treat malaria. The objective of this work was to conduct bioassay guided fractionation of the leaves of D. angustifolia using Plasmodium berghei infected mice. Method The antiplasmodial activity of the extracts and pure compounds was evaluated using the standard Peter's four-day suppressive method. The structures of...
متن کاملAntiplasmodial Activity of Ethanol Extract of Vernonia amygdalina leaf in Plasmodium berghei Infected Mice: in vivo study
The antiplasmodial activity of crude ethanol extract of Vernonia amygdalina leaf in Plasmodium berghei infected mice was evaluated. A total of 20 mice were randomly distributed into five groups of four mice each. The infected mice were treated immediately after inoculation with 200, 400 and 600mg/kgbw of the extract respectively. Group 4 (Positive control) was treated with standard drug (Chloro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Complementary and Alternative Medicine
سال: 2014
ISSN: 1472-6882
DOI: 10.1186/1472-6882-14-462