Antitumor activity of recombinant RGD-IFN-α2a-core fusion protein in vitro
نویسندگان
چکیده
منابع مشابه
Antitumor activity of recombinant RGD-IFN-α2a-core fusion protein in vitro
Interferon (IFN) regulates immune responses and antitumor activity. Arginine-glycine-aspartic acid (RGD) peptides can specifically bind to integrin αvβ3, a transmembrane receptor that is highly expressed on the surface of various cancer cells. In this study, we expressed recombinant RGD-IFN-α2a-core fusion proteins and assessed their antitumor activity in vitro. Two RGD-IFN-α2a-core fusion prot...
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ژورنال
عنوان ژورنال: Anti-Cancer Drugs
سال: 2017
ISSN: 0959-4973
DOI: 10.1097/cad.0000000000000421