Anxiety and Stress. Animal models of 'anxiety'.
نویسندگان
چکیده
منابع مشابه
Animal models of anxiety disorders and stress.
Anxiety and stress-related disorders are severe psychiatric conditions that affect performance in daily tasks and represent a high cost to public health. The initial observation of Charles Darwin that animals and human beings share similar characteristics in the expression of emotion raise the possibility of studying the mechanisms of psychiatric disorders in other mammals (mainly rodents). The...
متن کاملAnimal Models and Endophenotypes of Anxiety and Stress Disorders
An important criterion for developing animal models to study psychopathology involves establishing the validity of the model as a true representation of the process being studied. Generally, three types of validity are applied to animal models: face validity, construct validity, and predictive validity (1–3). Face validity refers to the outward similarity in appearance between the model and the...
متن کاملGenetic Animal Models of Anxiety
Conditions such as generalized anxiety disorder, panic disorder, social phobia, specific phobia, obsessive-compulsive disorder, and post-traumatic stress disorder cause undue suffering and economic burden on a substantial portion of our society. The prevalence and serious debilitating effects of anxiety disorders increases the necessity for fast and efficacious understanding of the neurobiologi...
متن کاملAnimal models of anxiety: an ethological perspective.
In the field of anxiety research, animal models are used as screening tools in the search for compounds with therapeutic potential and as simulations for research on mechanism underlying emotional behaviour. However, a solely pharmacological approach to the validation of such tests has resulted in distinct problems with their applicability to systems other than those involving the benzodiazepin...
متن کاملAnimal models of anxiety in mice.
Among the multiple possibilities to study human pathologies, animal models remain one of the most used pathways. They allow to access to unavailable answers in human patients and to learn about mechanisms of action of drugs. Primarily developed with rats, animal models in anxiety have been adapted with a mixed success for mice, an easy-to-use mammal with better genetic possibilities than rats. ...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 2000
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.115.5