Apathy But Not Diminished Expression in Schizophrenia Is Associated With Discounting of Monetary Rewards by Physical Effort

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Apathy but not diminished expression in schizophrenia is associated with discounting of monetary rewards by physical effort.

Negative symptoms in schizophrenia have been grouped into the 2 factors of apathy and diminished expression, which might be caused by separable pathophysiological mechanisms. Recently, it has been proposed that apathy could be due to dysfunctional integration of reward and effort during decision making. We asked whether apathy in particular is associated with stronger devaluation ("discounting"...

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BACKGROUND Negative symptoms of schizophrenia can be grouped in 2 dimensions: apathy and diminished expression. Increasing evidence suggests that negative symptoms are associated with altered neural activity of subcortical and cortical regions in the brain reward system. However, the neurobiological basis of the distinct symptom dimensions within negative symptoms is still poorly understood. Th...

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ژورنال

عنوان ژورنال: Schizophrenia Bulletin

سال: 2014

ISSN: 1745-1701,0586-7614

DOI: 10.1093/schbul/sbu102