Applying TADF Emitters in Bioimaging and Sensing—A Novel Approach Using Liposomes for Encapsulation and Cellular Uptake

A new method for facilitating the delivery, uptake and intracellular localisation of thermally activated delayed fluorescence (TADF) complexes was developed. First, confinement TADF in liposomes demonstrated, which were subsequently used as delivery vehicle cellular uptake. Confocal microscopy showed localise cytoplasm HepG2 cells. The procedures developed this work included removal molecular oxygen liposome preparation without disrupting structures. Time-resolved (point scanning) initial prompt followed by a weak, but detectable, component liposomal internalised By demonstrating that it is possible to deliver un-functionalised and/or unshielded complexes, sensing function TADFs, such oxygen, can be envisaged.