Aptamer-based liposomes improve specific drug loading and release
نویسندگان
چکیده
منابع مشابه
Reversible cell-specific drug delivery with aptamer-functionalized liposomes.
cis-Diamminedichloroplatinum(II) (cisplatin) is a potent chemotherapeutic agent for the treatment of a broad range of cancerous tumors. Despite its excellent antitumor efficacy, the major drawbacks of cisplatin include its lack of tumor specificity and severe side effects. In addition, certain tumor-cell types develop resistance to cisplatin from exposure to the drug. Strategies that allow the ...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2017
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2017.02.026