Arterial input function measurements for bolus tracking perfusion imaging in the brain
نویسندگان
چکیده
منابع مشابه
Arterial Input Function for Bolus Tracking Perfusion Imaging in the Brain
Elias Kellner, Irina Mader, Daniel Nico Splitthoff, Marco Reisert, Katharina Förster, Thao Nguyen-Thanh, Peter Gall, and Valerij G. Kiselev Department of Radiology, Medical Physics, University Medical Center Freiburg, D-79106 Freiburg, Germany, Section of Neuroradiology, Neurocenter of the Freiburg University Hospital, D-79106 Freiburg, Germany, Department of Cardiovascular Surgery, Albert-Ludw...
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Cerebral perfusion may be visualized by the dynamic imaging of an intravenously injected bolus (a few milliliters) of clinically approved gadolinium-containing contrast media. During its passage through the vasculature of the brain, the contrast agent induces magnetic field disturbances, which can be seen as signal loss on appropriately weighted dynamic MRI. This article deals with the quantita...
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Introduction: Quantification of cerebral blood flow (CBF) using bolus-tracking MRI is critically dependent on correct determination of the arterial input function (AIF) (1,2). The AIF is the concentration of tracer which enters the brain as a function of time. It is sampled in a supplying artery, which is often subject to a partial volume effect (PVE) due to the limited spatial resolution resul...
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Background Modern MRI myocardial perfusion protocols use rapid venous bolus injections, typically 3-5 ml/s of 5-15 ml of agent over a few seconds. The resulting arterial input functions are rapidly varying with high agent concentrations (Fig. 1A and 1B) and thus typically require high temporal resolution acquisitions (~1 sec), custom pulse sequences and complex processing methods for perfusion ...
متن کاملArterial spin labeling versus bolus-tracking perfusion in hyperacute stroke.
BACKGROUND AND PURPOSE Arterial spin labeling (ASL) is a perfusion magnetic resonance imaging (MRI) technique that does not require contrast administration and thus may be more practical in hyperacute stroke than susceptibility-weighted bolus-tracking perfusion-weighted imaging (PWI). However, a threshold for ASL measurement of the ischemic penumbra needs to be determined. METHODS A total of ...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2012
ISSN: 0740-3194
DOI: 10.1002/mrm.24319