Association Between 4q25 Variants, Risk of Atrial Fibrillation and Echocardiographic Parameters
نویسندگان
چکیده
منابع مشابه
Association between Variants on Chromosome 4q25, 16q22 and 1q21 and Atrial Fibrillation in the Polish Population
BACKGROUND Genome-wide studies have shown that polymorphisms on chromosome 4q25, 16q22 and 1q21 correlate with atrial fibrillation (AF). However, the distribution of these polymorphisms differs significantly among populations. OBJECTIVE To test the polymorphisms on chromosome 4q25, 16q22 and 1q21 in a group of patients (pts) that underwent catheter ablation of AF. METHODS Four hundred and t...
متن کاملassociation between echocardiographic indices and post coronary artery bypass graft surgery atrial fibrillation
results the mean age of patients was 60 ± 9.9 years. statistically significant relationship between the occurrence of af with mitral valve annulus, la volume index (lavi) , right ventricle function, and type of surgery (off pump or on pump) were detected in our study (p < 0.05) . there was no statistically significant relationship between the occurrence of af and time interval of p wave to a wa...
متن کاملAssociation Between rs2200733 Polymorphism on Chromosome 4q25 and Atrial Fibrillation in a Greek Population.
INTRODUCTION Atrial fibrillation (AF) is a common arrhythmia with evidence of genetic susceptibility. The rs2200733 single-nucleotide polymorphism (SNP) in a non-coding region on chromosome 4q25 has been associated with AF. The purpose of this case-control study was to examine the possible association of the rs2200733 polymorphism with AF in the Greek population. METHODS A total of 295 indivi...
متن کاملAssociation of Common Variations on Chromosome 4q25 and Left Atrial Volume in Patients with Atrial Fibrillation
AIMS Recent studies have shown that several genetic variants near the PITX2 locus on chromosome 4q25 are associated with atrial fibrillation (AF). However, the mechanism that mediates this association remains unclear. Basic murine studies suggest that reduced PITX2 expression is associated with left atrial dilatation. We sought to examine the association between single nucleotide polymorphisms ...
متن کاملLarge scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation.
AIMS A recent genome-wide association study identified a haplotype block on chromosome 4q25 associated with atrial fibrillation (AF). We sought to replicate this association in four independent cohorts. METHODS AND RESULTS The Framingham Heart Study and Rotterdam Study are community-based longitudinal studies. The Vanderbilt AF Registry and German AF Network (AFNet) are case-control studies. ...
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ژورنال
عنوان ژورنال: Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.
سال: 2020
ISSN: 2255-890X
DOI: 10.2478/prolas-2020-0001